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Importantly, the combination had a rapid onset with long duration and was equipotent to the positive controls pregabalin and morphine that have well-known motor impairing side effects which are absent for sEHI

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In this issue of the JCI, Li, Wang, et al

Dihexa is sold as a research chemical, not a supplement or approved drug, and is not for human consumption

Side Effects and Precautions Known Risks (Animal Studies + Anecdotal Reports) Potential for over-stimulation of neurogenesis , which is beneficial short-term but may carry unknown long-term risks Some users report: Mild headaches Irritability or emotional blunting Temporary insomnia if taken late in the day Theoretical Risk: Tumor Growth

J Am Chem Soc 95:27972803 Requejo R, Hurd TR, Costa NJ, Murphy MP (2010) Cysteine residues exposed on protein surfaces are the dominant intramitochondrial thiol and may protect against oxidative damage