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Thus, in many recent studies, the important role of HSP70 in the implementation of the mechanisms of metabolic adaptation, neuroplasticity and neuroprotection of brain cells is noted, which allows the presentation of HSP70 as a promising target for neuroprotective drug (Kampinga and Craig, 2010

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At the same time, we must be aware that hypervitaminosis E status may cause abnormal bleeding events by suppressing the synthesis of vitamin K-derived coagulation factors ( Throughout various studies, high doses of vitamin C have generally been observed to be well-tolerated

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Importantly, in KK-Ay diabetic mice, antibody-mediated neutralization of elevated IL-17 concentrations improved insulin resistance and increased glucose uptake by skeletal muscle, but not by adipose tissue (146)