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Human Monocytes and Macrophages Express Substance P and Neurokinin-1 Receptor

5.2 Parkinsons disease Parkinsons disease is the second most common chronic and late-onset neurodegenerative disease after Alzheimers disease, with clinical features including slowness of facial expression, increased muscle tension throughout the body, bradykinesia, progressive resting tremor, and dementia (Nishioka and Hattori, 2020)