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Graphical Abstract Keywords Drug hepatotoxicity, Acetaminophen, Lipid peroxidation, Oxidative stress, Ferroptosis, Glutathione peroxidase 4, Erastin, Ferrostatin-1, Methotrexate, Rifampicin, Isoniazid, Natural products Introduction Drug-induced liver injury (DILI) is a significant clinical problem worldwide

Docetaxel, a cytotoxic antimicrotubular agent, has been used in metastatic breast cancer treatment (Lyseng-Williamson and Fenton 2005)

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Figure 4 5.4 Anti-diabetic activity Natural products play a significant role in promoting human health (365, 366)

This article is for general educational purposes and is not a substitute for an in-person medical evaluation, diagnosis, or treatment

This preparation is commonly used to assist in the treatment of production stress, loss of appetite, and chronic wasting diseases in economic animals such as cattle and pigs