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Local injection site reactions are the most frequently reported side effects

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Vitamin B-12 is a water-soluble B complex vitamin that is present naturally in a variety of food sources such as fish, meat, and dairy products

The Risks of Vitamin B12 Injections Vitamin B12 shots carry the same risks as all other types of injection: A new, clean cannula should be used and the point of injection should be disinfected with alcohol, otherwise bacterial contamination is possible