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A single intradermal administration of MTB VAC resulted in protection of these animals against aerosol challenge of Mtb as observed by significantly reduced pathological damage as shown by in vivo medical imaging, gross pathology lesion counts and pathology scores (White et al., 2021)

A nasal spray sold in a multi-dose pump bottle at room temperature with no published accelerated stability data is a formulation where you cannot know what concentration of intact peptide you are actually delivering

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Most cases involve some combination of both components

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UVvis and circular dichroism spectroscopy have been used in kinetic studies to determine second-order rate constants for [2Fe-2S] cluster transfer from [2Fe-2S](GS 4 ) complex to acceptor proteins, such as human IscU, Schizosaccharomyces pombe Isa1, human and yeast glutaredoxins (human Grx2 and Saccharomyces cerevisiae Grx3), and human ferredoxins