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Klarna: Herausgeber: Klarna Bank AB (publ), Stockholm, Schweden

Mn is an essential metal found in many metalloproteins, including arginase, glutamine synthetase, pyruvate carboxylase, and MnSOD (Smith et al., 2010)

From the perspective of the pathogenesis of ferroptosis, in addition to abnormal metabolism of iron, amino acids, and lipid peroxides, several signaling pathways are involved in modulating ferroptosis, such as the p53-SAT1-ALOX15 pathway (Ou et al

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Some studies suggest that it may impair mitochondrial homeostasis, 279 whereas others indicate that it can promote mitochondrial function