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The first-line drug is carbamazepine (Tegretol) , and most patients respond well in the early phase

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5), and by inference, neurotoxic damage.53 Forgione and colleagues had previously hypothesized that GPX1 deficiency directly induces an increase in vascular oxidative stress, with attendant endothelial dysfunction.54 Glutathione peroxidases, particularly GPx1 have also been implicated in the development and prevention of many common and complex diseases, including cancer and cardiovascular disease (Fig

10.1212/WNL.0000000000005475 31 PfeifferS.KrgerJ.MaierhoferA.BttcherY.KltingN.El HajjN.et al (2016)

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