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Eryptosis is defined as an RCD modality of mature erythrocytes critically dependent on Ca 2+ signaling, associated with cell shrinkage, membrane blebbing, and PS externalization

Nature 584 , 353363 (2020)

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Vyvgart Hytrulo represents the first novel, precision mechanism of action in more than 30 years for CIDP, a rare, debilitating neuromuscular disorder of the peripheral nervous system, according to argenxs press release

4,54 In addition to the RING E3 ligase Pirh2, the WW-domain, HECT-containing, E3 ligase Itch/AIP4 bound within aa 397571 of the SAM domain of p63 and induced its ubiquitination and degradation

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