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Karlmark KR, Weiskirchen R, Zimmermann HW, Gassler N, Ginhoux F, Weber C, et al

319,321 Collectively, the ability of HSP70 and HSP90 to engage multiple aggregation-prone client proteins across distinct NDDs underscores their central role in neuronal proteostasis and highlights their broad therapeutic potential

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As a consequence, it has been reported that Cys-S conjugates cannot be converted to NAC-S conjugates in cultured skin cells and accumulate without being metabolized (Roser et al

Talked with the doctor and she recommended a cocktail of vitamins and other good stuff

Future research should focus on identifying stage-specific ferroptosis regulators, optimizing drug delivery to the CNS, and validating safety and efficacy in large-scale clinical trials