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885 MG differs fundamentally from PROTACs and other degraders by inducing degradation through promoting tight binding between the target protein and proteasome components, leading to the proteins subsequent degradation

Li, Z., Zhang, Z., Ke, L., Sun, Y., Li, W., Feng, X., Zhu, W., & Chen, S

In addition, the longitudinal PDSP expression scores are significantly different between the PD group and the control group at time points consistent with the pathophysiology of the animal model (4, 6, and 9 weeks after AAV injection)

doi: 10.3201/eid2208.151878 [DOI] [PMC free article] [PubMed] [Google Scholar] Jongen VH, van Roosmalen J, Tiems J, Van Holten J, and Wetsteyn JC (1997)

Experience ongoing symptoms despite oral supplements

It does not naturally occur in plant-based foods so vegetarians can find it in some breakfast cereals or use B12 oral supplements or B12 injections