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The phrase "specifically binds" refers to, for example, an antibody that binds to an epitope or antigen or antigenic determinant in the following manner: the binding may be replaced by or competed with a second agent having the same or similar epitope, antigen or antigenic determinant

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Similar mechanisms are proposed in HD, where mHTT induces mitochondrial fragmentation and oxidative damage, promoting NLRP3-driven inflammation [115]