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Artesunate induces cell death in human cancer cells via enhancing lysosomal function and lysosomal degradation of ferritin

Generally, intrinsic stresses such as elevated cytosolic Ca2+, oxidative stress, DNA damage, hypoxia and survival factor deprivation, are known to activate the intrinsic apoptotic pathway

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The region where the patient is located is also important because the diet of people in different regions is not consistent