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In the myocardium of old mice, Nrf2 transcriptional activity was reduced, but it could be restored by moderate exercise [62]

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The biology and enzymology of eukaryotic protein acylation

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In fact, a 2023 paper published in the Journal of Cerebral Blood Flow & Metabolism reported that methylene blue (in similar doses studied by researchers at The University of Texas at Austin who claimed the compound had memory-enhancing properties) led to a 8% decrease in human brain blood flow

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doi: 10.1016/j.addr.2022.114296 [DOI] [PubMed] [Google Scholar] 41

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Fenofibrate, a ligand for PPARalpha, inhibits aromatase cytochrome P450 expression in the ovary of mouse

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W.HertigA

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