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These examples clearly indicate that the activation of STAT3 signaling is able to trigger cellular senescence, probably in co-operation with NF-B and SMAD3 signaling

doi: 10.3389/fnagi.2019.00177 Received 28 February 2019 Accepted 02 July 2019 Published 08 August 2019 Volume 11 - 2019 Edited by Anne Eckert, University Psychiatric Clinic Basel, Switzerland Reviewed by Patrizia Giannoni, University of Nmes, France

D., Kim, C

Kalaras MD, Richie JP, Calcagnotto A, Beelman RB

Exendin-4 Enhances Proliferation of Senescent Osteoblasts Through Activation of the IGF-1/IGF-1R Signaling Pathway

In addition, the GPx defends against oxidants that cause neuronal and protein damage, which reduce H 2 O 2 and lipid peroxide to water and alcohol, respectively