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doi: 10.3389/fnins.2015.00189

Chronic ketamine exposure in rodent models (50 mg/kg daily for 8 weeks) leads to significant activation of microglial cells and elevated expression of proinflammatory cytokines, such as IL-6 and IL-1, which correlate with hippocampal neuronal damage (Yin et al., 2022)

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Laboratory Investigation, 96 (4), 378390

SNAC functions through a multifaceted mechanism: it buffers the local gastric pH, thereby protecting semaglutide from acidic degradation and proteolytic enzymes, and enhances drug solubility and monomerization