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This support the nephroprotective role of Spirulina reported by previous studies [72,73,74]

& Loeb, L

The following conditions for the ion transfer were used: 4500 V capillary voltage, 500 V endplate offset, 4 L/min dry gas at 200 C, 1.8 bar nebulizer pressure and 10 eV collision energy

Endothelial dysfunction and prothrombotic reprogramming Endothelial cells (ECs) exposed to NET components undergo profound functional reprogramming, shifting from physiological vascular homeostasis toward inflammationdriven endothelial injury and a procoagulant phenotype [78]

This interaction may facilitate the formation of -sheet-rich tau fibrils, contributing to synaptic failure, neuronal death and cognitive decline observed in patients with AD (199)