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The gut harbors its own immune system, which is called intestine and gut-associated lymphoid tissue (GALT), key for whole body immune function

We observed significant decreases in gene expression of NADPH quinone dehydrogenase 1 (Nqo1), glutamate-cysteine ligase catalytic subunit (Gclc), glutathione S-transferase mu-1 (Gstm1), glutathione peroxidase 1 (Gpx1), glutathione peroxidase 4 (Gpx4), and heme oxygenase-1 (Hmox1) in the CC of CSE -/- mice relative to WT littermate controls (Figure 5B)