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Parmi les effets indsirables possibles, on trouve: Nauses et Vomissements: Des rapports anecdotiques suggrent que la prise de supplments de glutathion pourrait provoquer des maux d'estomac, des nauses et des vomissements chez certaines personnes

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Although studies have shown that Nrf2 and Nrf2-activating chemicals have opposing effects on the NLRP3 inflammasome that are not dependent on Nrf2-mediated gene expression, both effects are independent of the transcriptional activity of Nrf2 [129]