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Description

This was confirmed by quantification of the 4HNE positive area per relative distance within reconstructed liver lobules in whole slide liver images (see Supplementary Methods

The kynurenine pathway of tryptophan metabolism was observed to activate in COVID-19 patients (Lionetto et al., 2021), which is involved in regulating inflammation and immune tolerance

N -(5-(((5-( tert -butyl)oxazol-2-yl)methyl)thio)thiazol-2-yl)-1-(8-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)thio)octyl)piperidine-4-carboxamide ( 24 )