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Success will require sustained investment in basic research to understand fundamental mechanisms, clinical research to test therapeutic hypotheses, and technological development to enable precision metabolic medicine

Mitochondria are the power centers of your cells

Compound I can either be reduced to the resting state by oxidizing (pseudo)halogens or go through the peroxidase pathway to Compound II: The halogenation cycle is unique to MPO in terms of its ability to oxidize chloride