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As shown in Supplemental Figure 5, B and C, we observed lower Na/K/Cl cotransport and Na/H exchange activities in RBCs from mitapivat-treated 4.2 / mice when compared with vehicle-treated animals, suggesting an improved RBC ion homeostasis related to the amelioration of RBC membrane mechanical stability

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RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals

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Dendritic cells (DCs) act as central hubsIRE combined with VMT/CaO 2 NSs captures tumor antigens to form in situ vaccines that promote DC migration (105)