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Sherratt PJ, Huang HC, Nguyen T, Pickett CB

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[DOI] [PMC free article] [PubMed] [Google Scholar] 200.Zang T.M., Hollman D.A., Crawford P.A., Crowder M.W., Makaroff C.A

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An oft-highlighted conceptual challenge is that while SSRI medications rapidly and reliably elevate synaptic levels of serotonin, therapeutic effects are only observed after a period of two or more weeks, suggesting that monoamines are not by themselves causative