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This increase in circulating GH and IGF-1 levels supports: Enhanced muscle protein synthesis Activation of satellite cells , driving muscle repair and hypertrophy Improved muscle strength and work capacity Pulsatile increases in GH and IGF-1 via GHRP-2 promote hypertrophy by stimulating mTOR activation and enhancing muscle anabolic processes. Schenk , American Journal of Physiology For athletes seeking lean muscle gains without excessive appetite stimulation, GHRP-2 offers a superior profile to GHRP-6

Evidence from rabbit models indicates that Src and Lck act downstream of PKC and may cross-talk with the NO pathway during IPC [179, 220]

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