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10.3389/fnut.2020.00143 Front Nutr

hUC-MSCs improved ovarian function in CTX-induced POI mice by activating the nuclear-related factor-2 (Nrf-2) antioxidant pathway, enhancing iron metabolism (Nrf-2/ ferritin heavy chain 1(FTH1)), and promoting the antioxidant response (Nrf-2/ glutathione peroxidase 4 (GPX4)), thereby inhibiting ferroptosis [116]

10.1073/pnas.0403412101 Proc

A critical mechanistic link between inflammation and depression involves activation of the indoleamine-2,3-dioxygenase (IDO) enzyme, which diverts tryptophan metabolism away from serotonin production toward the kynurenine pathway

PE-22-28 raises seizure threshold concerns via TREK-1 blockade Evidence integrity : Dihexa has a retracted key publication

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