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Kolomin T, Shadrina M, Slominsky P, et al

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Clinical and nutritional benefits of cysteine-enriched protein supplements

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For example, opioids decrease pulmonary perfusion via hypoxia-induced pulmonary vasoconstriction 143 , and by direct pulmonary vasoconstriction 144,145 by mechanisms including centrally-mediated activation of sympathetic nerve activity to the lungs 146 , and induction of histamine release in the lungs 144,147

By targeting the vasculature that supports white adipose tissue, it appears to interrupt some of the metabolic dysfunction associated with obesity at a fundamental level