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In a transgenic mouse expressing low GSH levels (Gclm KO), we found reduced number of prefrontal and hippocampal PV-immunoreactive interneurons together with diminished high-frequency neuronal synchronization [81, 82], reduced number of PV-immunoreactive neurons in thalamus reticular nucleus together with altered firing properties [56], thus demonstrating the functional consequence of a redox dysregulation

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Afterwards (D3-D4), cells were split using the Trypsin/EDTA solution (BioWest) and seeded for experiments

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Pretreatment with black cumin seed ethanolic extract (800 mg/kg) exhibited a promising cardioprotective action against isoproterenol-induced myocardial infarction by improving cardiac biomarkers and antioxidant status [144]