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The authors show that adipose de novo lipogenesis is supported by glucose, and the pentose phosphate pathway provides NADPH, while hepatic lipogenesis mainly uses acetate and lactate, with NADPH generated by folate-mediated serine catabolism

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The right way to understand it is as a next-generation amylin analogue with promising clinical data, unresolved regulatory status, and clear differences from semaglutide, tirzepatide, and retatrutide

Conclusion: Y90 TARE is a safe and effective treatment modality however 5% of patients have worsened liver function after treatment