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Shehata AI, Shahin SA, Elmaghraby AM, Alhoshy M, Toutou MM, Soliman AA, Amer AA, Habib YJ, Gewaily MS, Teiba II, El Basuini MF (2024) Stevioside mitigates lead toxicity in thinlip mullet juveniles: Impacts on growth, metabolism, and immune function

The ability of IL-1 to induce chondrocyte catabolism [121] has been well known for a long time, but it is only recently that IL-1 has been shown to disrupt chondrocyte iron homeostasis [117] and trigger chondrocyte ferroptosis [22, 122]

Inhibition of system xc(-) transporter attenuates autoimmune inflammatory demyelination

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Animal experiments have demonstrated that high-fat diet downregulates tight junction protein expression (such as occludin and ZO-1), reduces mucus layer thickness, and increases intestinal permeability ( Metabolic endotoxemia refers to a state of chronically elevated circulating LPS levels caused by diet (particularly high-fat diet) (92) first proposed this concept, finding that high-fat diet mice exhibited significantly elevated plasma LPS levels accompanied by increased Gram-negative bacteria proportions and enhanced intestinal permeability

Developmental toxicity 7.5.1