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Purification is typically performed using high-performance liquid chromatography, and analytical verification methods such as mass spectrometry are used to confirm peptide identity

This paper found that KEAP1-mutant tumours are sensitive to oxPPP inhibition

This intensity gated systemic redox signaling model is illustrated in Figure 6, where the signal is released into the blood stream in response to the high intensity exercise and activates Nrf2 signaling in the contralateral unstimulated muscle, while low intensity muscle stimulation does not meet the threshold to propagate a systemic redox signaling response

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Under 50 J/cm 2 exposure, 4-HNE-protein adduct levels increased by up to approximately sevenfold compared to dark controls, accompanied by a marked rise in intracellular ROS