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The pharmaceutical formulation disclosed herein may comprise hydroxypropyl- alpha-cyclodextrin having a minimum of about 0.4 hydroxypropyls per glucose unit

However, when cells are infected with coronavirus, there is a reduction of ACE2 receptors on the cell surface and this results in an increase of Ang II which binds to ACE1 and increases ROS levels through NADPH oxidase (Nguyen Dinh Cat et al., 2013)

doi: 10.14499/indonesianjpharm30iss3pp147 90

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Godlewska BR, Clare S, Cowen PJ, Emir UE