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Here, we pharmacologically targeted the mitoribosome to induce aberrant mitochondrial translation (mistranslation) resulting in m ablation and inhibit mitochondrial translation (nontranslation) resulting in subsequent loss of OXPHOS complexes, in order to identify pathways increasing cell fitness

3.4.4 Recovery and matrix effect The matrix effect of all plasma samples ranged between 86.26% and 114.26%, while that of the brain samples ranged from 91.58% to 112.50%

This prompted Marks to devise a simpler method

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Plant Physiol 166:528