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Examples include Tryptyr (acoltremon) , a first-in-class TRPM8 thermoreceptor agonist indicated for the treatment of the signs and symptoms of dry eye disease, and BRINSUPRI (brensocatib) , a first-in-class oral DPP1 inhibitor for non-cystic fibrosis bronchiectasis (NCFB), offering new treatment options for diseases that previously lacked effective therapies

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Menthol is commonly used in topical creams and gels for pain relief

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HGF 10 ng ml Dihexa or Nlel-AnglV 10 "12 M a combination of sub-threshold doses of 2.5 ng/ml HGF + 10 "12 M Dihexa or 2.5 ng/ml HGF + 10 "12 M Nlel-AnglV The results are presented in Figure 12 A and B

Sikiric P, Hahm KB, Blagaic AB, et al