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Marxsen JH, Stengel P, Doege K, Heikkinen P, Jokilehto T, Wagner T, Jelkmann W, Jaakkola P, Metzen E

That is the mechanistic case for the blend in one paragraph and it is exactly why the two are described as complementary rather than redundant

Small number of research groups : A limited number of research groups have conducted most studies, which may affect the generalizability of the results

Although quite rare, B12 may aid in repairing the myelin sheath depending on the underlying cause of the neuropathy

Some patients may experience mood changes or anxiety, which could be related to changes in eating patterns, blood glucose levels, or direct pharmacological effects