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Importantly, when we compared OxPhos signalling in the same way to patients who did not receive 5FU-based chemotherapy treatment in the same cohort ( n = 90), we observed no difference in survival (Extended Data Fig

We explained that the proposed adjustments would remove improper payments from the performance year expenditures and factors used to calculate updated historical benchmarks, among other financial calculations, that resulted in inaccuracies in an ACO's payment determination, including the amount of shared savings CMS paid an ACO or the amount of shared losses owed to CMS by an ACO participating under a two-sided model

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