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When GH is released in timed pulses rather than maintained at steady-state levels, it produces meaningfully different metabolic effects including better fat oxidation and a more favourable interaction with insulin sensitivity than continuous elevation does

Howells LM, Sale S, Sriramareddy SN, Irving GR, Jones DJ, Ottley CJ,

Even Skin Tone: Some studies suggest GHK-Cu can improve skin clarity and reduce hyperpigmentation, contributing to a more even skin tone

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Thompson et al., 2020)

One such important cell surface protein consisting of highly conserved cysteine residues is connexin 43 (Cx43)a widely expressed gap junctional protein important for cell death, proliferation and differentiation [45]