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Anti-Inflammatory and Endothelial Effects Preclinical studies have shown that vitamin C influences several key molecular pathways, including NLRP3/caspase-1 [50], TLR4/MyD88/NF-B [51], Nrf2/HO-1 [52], and MAPK [53]

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Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice