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Oxidized Redox State of Glutathione in the Endoplasmic Reticulum

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After the addition of 5 L of Annexin V-FITC, the cells were incubated at room temperature for 15 min

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Oxidative stress can promote the production of inflammatory cytokines, and free radicals can react with protein, lipids, nucleic acids and other cellular macromolecules, playing an important role in the pathogenesis of RA (197)

found that PDT treatment of colorectal cancer cells with a photosensitizer that specifically targets mitochondria induced elevated levels of mitochondrial ROS in the cells and induced colorectal cancer cells pyroptosis via the caspase 3/gasdermin E pathway