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Mechanistic studies probing single-residue substitutions in this scaffold have helped map which positions are responsible for the cortisol- and prolactin-sparing profile

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For a deeper understanding, the cancer cells were preincubated with NAC and the presence of ROS upon treatment were assessed using the ROS specific probe DCFH-DA

EFS was 61% and 62% when the donor was MRD or MUD (p=0.82)

The LC group received 350 mg/kg LC, the TMZ group received 15 mg/kg TMZ, the AP group received 5 mg/kg AP gavage 1 h prior to modeling, and the other groups received saline

Short term treatment with a cocktail of rapamycin, acarbose and phenylbutyrate delays aging phenotypes in mice