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The SCIEX OS software (version 1.6, AB SCIEX, MA, USA) was applied for metabolite identification and concentration calculation

In contrast, glutathione reductase (GR) activity was significantly reduced in both groups compared with reference values, with a more pronounced decrease observed in unvaccinated patients

This is why oral dosages are almost always higher than injectable ones to achieve a comparable systemic effect

Peptides and proteins were identified with a 1% false discovery rate (FDR) (Tang et al., LC-MS/MS Analysis in MRM Mode LC-MRM experiments were performed on an identical LC platform and column, and a QTRAP 5500 (Sciex, Concord, ON) hybrid quadrupole-linear ion trap system with a TurboIonSpray ion source in positive mode

Each route impacts how quickly the compound is absorbed, distributed, and eliminated