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Role of Glutathione in Cancer: From Mechanisms to Therapies Stimulation of de novo glutathione synthesis by nitrofurantoin for enhanced resilience of hepatocytes Cell Biology and Toxicology Springer Nature Link Differentiating Changes in Glutathione Levels from Cytotoxic Events Using Multiplexed Assays Glutathione responsive molecularly imprinted polymer based precision delivery system for the synergistic treatment of anti metabolism and chemodynamic therapy in tumor ScienceDirect Facile Hydrophobication of Glutathione Protected Gold Nanoclusters and Encapsulation into Poly(lactide co glycolide) Nanocarriers Scientific Reports Catabolism of extracellular glutathione supplies cysteine to support tumours Nature

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Table 2 Metabolic alterations in neurodegenerative diseases

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Studies from human autopsies or animal models have revealed that MPO from these cells is associated with Alzheimer's disease, multiple sclerosis, stroke or cerebral ischemia, Parkinson's disease, depression or bipolar disorder, bacterial meningitis, neuroinflammation, and epilepsy (reviewed in [107])

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The bottom line on human data: promising signals, no randomized controlled trials, and no long-term safety data in humans

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