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Riluzole was US Food and Drug Administration (FDA) approved to treat amyotrophic lateral sclerosis in 1994 and is approved for this indication by multiple regulatory agencies [Canadas Therapeutic Products Directorate (TPD), European Medicines Agency (EMA), Australias Therapeutic Goods Administration (TGA)] [81,82,83]

Telomerase activation also creates an unresolved safety concern

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Amphiregulin promotes hair regeneration of skin-derived precursors via the PI3K and MAPK pathways

HER2-negative cancer cells dont have unusually high levels of this protein