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Hydroalcoholic leaf extract of Isatis tinctoria L

This method is based on the inhibition of pyrogallol auto-oxidation, the colour intensity of which can be determined at 570 nm

Functionally, Epithalon is hypothesized to exert its biological effects primarily through the activation of telomerase, an enzyme that adds specific DNA sequence repeats (TTAGGG in all vertebrates) to the 3 end of DNA strands in the telomere regions, which are found at the ends of eukaryotic chromosomes

Patients with HIV infection, with hepatitis B or C virus, and those with cirrhosis are at increased risk from antiretroviral therapy and decompensation by toxic drugs

Tros de Ilarduya MC, Martn C, Goi MM, Martnez-Ohrriz MC

doi: 10.1016/j.tplants.2020.09.001 110 SakakibaraH