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This acquired immunodeficiency could also justify the lytic or abortive reactivation of this and other latent pathogens, such as other herpesviruses and Parvovirus B19, that occurs in patients with ME/CFS [9, 10, 15, 17, 34, 361363] and could generate, on the one hand, the production of transient autoantibodies such as ANCAs, ANAs, or antiphospholipid antibodies (such as anticardiolipin) [71, 360], causing exacerbation of symptoms, and on the other hand, the increased release of viral dUTPases that increase neurological symptoms [10, 11, 26], generating more inflammation and disease flares

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This disability often arises due to the skeletal muscle wasting that can occur with acute periods of disuse, such as during hospitalization or illness

Von der eigenen Nutzung wird daher explizit abgeraten