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(Mechanistic rationale aligns with the literature above.) PMC+1 For longer-term metabolic health, periodically track liver enzymes, lipids, glucose/insulin metrics, and, per standard guidelines, follow age-appropriate bowel cancer screening

Cells characterized by rapid division (e.g., epithelial cells, bone marrow, myeloid cells) appear to have the greatest requirement for vitamin B 12

Moreover, starvation-induced autophagy is mediated by attenuating the interaction between apoptosis-related protein B cell lymphoma 2 (Bcl-2), basal cell lymphoma extra-large (Bcl-X L ) and Beclin-1 (Atg6) (Kadry et al