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The authors noted NNMT overexpression in many human malignancies and described 5-Amino-1MQ as a novel NNMT inhibitor with promising results across obesity and cancer cell research models

A common variant, C677T , can reduce this conversion by up to 70% in people with two copies of the mutation (Frosst et al., 1995)

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In adults and older children, the total volume used should also stay within safe limits animal studies suggest up to about 30 mL (the full vial) can be given to an adult without benzyl-alcohol toxicity, but one should still use only the amount needed and discard the rest if sterility is lost