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Aging Cell (2015) 14:9213

Consequently, choline and betaine methylated the promoter region of PPAR-, suppressing mRNA expression and possibly the lipogenic actions of the encoded protein

10.1016/j.pmrj.2015.08.010 81 UkebaD.YamadaK.TsujimotoT.UraK.NonoyamaT.IwasakiN.et al (2021)

For a pathogen to continue to exist, it must put itself in a position to be transmitted to a new host, leaving the infected host through a portal of exit