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Since this disease is prone to intracranial or distant metastasis and poses a serious threat to children's lives, researching its pathogenic mechanism and treatment targets has always been a top priority in ophthalmic research

This seems to be the most sensitive indicator of a delicate imbalance with glutathione and other factors needed to recycle vitamin C

[DOI] [PMC free article] [PubMed] [Google Scholar] 354.Xiong, X

In another embodiment, a PNA may be modified, for example to enhance its stability or cellular uptake, by: by attaching lipophilic or other ancillary groups to the PNA, by forming PNA-DNA chimeras, or by using liposomes or other drug delivery techniques known in the art

J Biol Chem 1998a;273:1605866