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The moiety -L-D of formula (VIII) can be prepared following procedures that are known in the art of organic synthesis (chemical reactions, extraction, evaporation, precipitation, chromatography, filtration, trituration, crystallization, and the like), and analytical procedures, which are known to persons of ordinary skill in the art of analytical chemistry

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While some studies have demonstrated that machine learning approaches can classify PD-associated microbiota patterns with reasonable accuracy, these models do not imply the existence of a uniform or reproducible microbial signature

However, RT-qPCR results demonstrated significant increases in mRNA expression levels of genes associated with pluripotency and cell proliferation, such as OCT4, NANOG, and SOX2, in the Leo20 group

Abu-Sbeih, H, Szafron, D, Elkafrawy, AA, Garcia-Rodriguez, V, Ma, W, Xu, A, Khurana, S, Numan, L, Chen, E, Goldstein, R, Tsen, A, Peng, Y, Blum Murphy, M, Kopetz, S , Ikoma, N, Shatila, M, Qiao, W, Raju, GS, Ross, WA, Ge, PS, Coronel, E, Wang, Y