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When cells are exposed to oxidative stress, the conformation of Keap1 changes, allowing Nrf2 to stabilize and translocate into the nucleus, where it activates the expression of a series of antioxidant genes 28

Current Opinion in Supportive and Palliative Care , 7(4), 345-350

GAO/PEMD-92-3

Figure 1 ) was generally used as an adjunct to standard medical therapy, not in place of it

They might start with 1,000 mcg daily for a week

In this sense, scientific community is searching for new alternative noninvasive techniques or biomarkers for asthma phenotypes identification, treatment monitoring, exacerbations prediction, differential diagnosis of other pathologies with similar symptoms and personalized diagnosis when patients suffer from comorbidities such as rhinosinusitis or other atopic disorders 6,22,23